Webinar: Leveraging metagenomics with qPCR-based assays to better understand the canine gut microbiome
In this webinar, Jan Sucholdolski, DVM, Ph.D., of Texas A&M University, and Jean Macklaim, Ph.D., of Diversigen, will describe the strengths and limitations of two approaches, the untargeted discovery-based approach of shotgun metagenomic sequencing...
The canine gut microbiome plays an important role in host health and disease. Understanding its composition and function can aid in the development of new therapies and diagnostic tools.
In this webinar, Jan Sucholdolski, DVM, Ph.D., of Texas A&M University, and Jean Macklaim, Ph.D., of Diversigen, will describe the strengths and limitations of two approaches, untargeted discovery-based approach of shotgun metagenomic sequencing with a targeted qPCR-based assay for the canine gut microbiome, called the dysbiosis index, to elucidate underlying host-microbe interactions. Metagenomics sequencing facilitates exploratory discoveries, however, unlocking these discoveries requires adequate assignment of sequencing reads to reference genomes. Our ability to annotate using currently available reference databases composed mainly of human-relevant microbes is limited, leaving a large proportion of canine-specific microbiome sequences unidentified.
To address this, Diversigen developed a specialized metagenomics service (MetaGene™ Canine) based on a comprehensive, species-specific database to provide greater insight. We also discuss how MetaGene™ Canine can integrate additional canine information tailored to your research area for a more powerful and complete understanding of the microbiome.
This webinar is sponsored by Diversigen and is presented by Petfood Industry.
